中心主任

奚廷斐

副主任

郑裕东官月平

成员

奚廷斐刘国权

朱思泉

郭志猛郑裕东

官月平王国杰

王丽萍王金伟

邵慧萍、海明潭

   高瑾

顾问

卢世璧院士、付小兵院士

王迎军教授、樊瑜波教授

 
 
 

 

 

官月平

通信地址: 北京市海淀区学院路30号
邮       编: 100083
办公地点: 北京科技大学主楼181
电       话: 010-62333945
邮       箱: ypguan@mater.ustb.edu.cn

 

 

 

个人简历
  教授,博士生导师。2000年在中国科学院过程工程研究所获得博士学位,2000—2006年留在该研究所生化工程国家重点实验室从事科研工作,其中2001—2003年在德国Karlsruhe研究中心技术化学研究所(Institute for Technical Chemistry, Forschungszentrum Karlsruhe )做博士后研究。2006年调入北京科技大学材料科学与工程学院生物医用材料研究室工作。

主要研究方向
  生物医用磁性纳米材料和器件有关的科学研究和技术开发工作。
  研究内容包括:有机包覆磁性纳米颗粒的制备、超顺磁性聚合物纳米/微米球的合成,表面化学修饰和生物修饰、磁性生物传感器、高梯度磁性分离理论和装置设计等;
  实际应用例如:天然产物、基因重组药物蛋白规模化磁性分离技术、疾病诊断用磁性纳米载体和磁性纳米标记材料、磁性纳米靶向药物输送载体的设计与组装技术、食品和环境微生物快速检测磁性纳米材料及磁性生物传感器、中药有效药用活性组分的磁性分离技术及磁性分离装置设计等。
  此外,还研究合成了磁性胶体、磁性无机纳米复合颗粒、磁性有机纳米复合颗粒、磁性活性炭纳米颗粒等材料,应用于磁性催化剂载体、核废水处理、贵金属回收等领域。

 

     

 

近五年主要负责承担的科研项目
[1] 国家863计划新材料领域纳米专项课题“丙肝病毒快速检测磁性纳米材料及磁性生物传感器”(2007—2010,课题负责人);
[2] 国家重点基础研究发展计划(973计划)子课题“磁性分离技术用于提取贵金属的探索性研究”(2007—2011,子课题负责人);
[3] 北京市自然科学基金项目“高蛋白质吸附容量磁性载体的制备及生物分离应用研究”(2007—2009,课题负责人);
[4] 首都医学发展科研基金项目“人血清丙肝病毒抗原磁性免疫检测系统的研究和临床意义”(2008—2011,子课题负责人);
[5] 中国科学院科研信息化专项课题“磁性颗粒专题科学数据”(2009—2010,子课题负责人);
[6] 国家自然科学基金面上项目“磁性纳米颗粒技术分离模拟高放废液中锶的研究”(2005—2007,子课题负责人);
[7] 企业合作项目“磁性聚合物微球材料和还原型谷胱甘肽分离”(2006—2007,课题负责人);
[8] 国家863计划纳米专项课题“生物分子分离磁性纳米材料和技术”(2003—2005,课题组副组长);
[9] 中石油合作开发项目“ Pt、Pd催化剂在磁性氧化铝载体表面纳米化负载技术”(2004—2006,课题负责人);
[10] 与德国Karlsruhe研究中心国际合作研究项目“纳米磁性载体分离中药提取物中的有效药用活性组分”(2004—2007,项目中方联系人);

近五年发表的代表性研究论文
[1] Mahmood Irama, Chen Guo, Yueping Guan, Ahmad Ishfaq and Huizhou Liu, Adsorption and magnetic removal of Neutral red dye from aqueous solution using Fe3O4 Hollow Nanospheres, Journal of Hazardous Materials, 2010, (in press available online at www.sciencedirect.com ).
[2] Feng Qu, Yueping Guan, Zhiya Ma and Qiang Zhang,Synthesis of Cibacron Blue F3GA-coupled Magnetic PMMA Nanospheres and Their Use for Protein Affinity Separation,Polymer International,2009,58(8),888-892.
[3] Chengli Yang, Yueping Guan, Jianmin Xing, and Huizhou Liu; Surface Functionalization and Characterization of Magnetic Polystyrene Microbeads; Langmuir, 2008, 24 (16), 9006–9010
[4] Chengli Yang, Yueping Guan, Jianmin Xing, Guobin Shan and Huizhou Liu, Preparation and characterization of monodisperse superparamagnetic poly(vinyl alcohol) beads by reverse spray suspension Crosslinking; Journal of Polymer Science Part A-Polymer Chemistry, 2008, 46 (1), 203-210
[5] Lin Chen, Chen Guo, Yueping Guan and Huizhou Liu, Isolation of lactoferrin from acid whey by magnetic affinity separation, Separation and Purification Technology, 2007, 56 (2), 168-174.
[6] Xiaoying Guo/Yueping Guan, Bin Yang , Yongning Wang , Hualong Lan , Wentang Shi, Zhenghui Yang and Zuhong Lu,Enzyme Chemiluminescence Immuno Assay of Free hCGβ in Serum Based on Superparamagnetic Polymer Microbeads,Int. J. Mol. Sci. 2006, 7, 274-288
[7] Chengli Yang, Yueping Guan, Jianmin Xing, Huizhou Liu, Development of superparamagnetic multifunctional carriers and application for affinity separation of subtilisin Carlsberg, Polymer, 2006, 47(7), 2299-2304.
[8] Xianqiao Liu, Michael D. Kaminski, Yueping Guan, Haitao Chen, Huizhou Liu and Axel J. Rosengart, Preparation and characterization of hydrophobic superparamagnetic magnetite gel, Journal of Magnetism and Magnetic Materials, 2006, 306 (2),248-253.
[9] Chengli Yang, Jianmin Xing, Yueping Guan, Huizhou Liu, Superparamagnetic poly(methyl methacrylate) beads for nattokinase purification from fermentation broth, Applied Microbiology and Biotechnology, 2006, 72(3), 616 - 622
[10] Zhiya Ma, Yueping Guan and Huizhou Liu,Affinity adsorption of albumin on Cibacron Blue F3GA-coupled non-porous micrometer-sized magnetic polymer microspheres, Reactive & Functional Polymers, 2006,66 (6),618-624
[11] Zhiya Ma, Yueping Guan and Huizhou Liu,Superparamagnetic silica nanoparticles with immobilized metal affinity ligands for protein adsorption,Journal of Magnetism and Magnetic Materials, 2006, 301 (2), 469-477
[12] Zhiya Ma, Xianqiao Liu, Yueping Guan and Huizhou Liu, Synthesis of Magnetic Silica Nanospheres with Metal Ligands and Application in Affinity Separation of Proteins, Colloids & Surfaces A , 2006, 275 (1-3) , 87-91
[13] Chengli Yang, Yueping Guan, Jianmin Xing and Huizhou Liu,Synthesis and protein immobilization of monodisperse magnetic spheres with multifunctional groups, Reactive & Functional Polymers, 2006,66 (2): 267-273
[14] Chengli Yang, Yueping Guan, Jianmin Xing, Junguo Liu, Zhentao An, Huizhou Liu, Preparation of Magnetic Polystyrene Microspheres with a Narrow Size Distribution, AIChE Journal, 2005, 51(7), 2011-2015.
[15] Zhiya Ma, Yueping Guan, Xianqiao Liu and Huizhou Liu, Synthesis of Magnetic Chelator for Immobilized Metal Affinity Adsorption of Protein with High Adsorption Capacity by Cerium Initiated Graft Polymerization, Langmuir, 2005, 21, 6987-6994.
[16] Zhiya Ma, Yueping Guan, Xianqiao Liu and Huizhou Liu, Synthesis and Characterization of Micron-sized Monodisperse Superparamagnetic Polymer Particles with Amino Groups, Journal of Polymer Science Part A: Polymer Chemistry, 2005, 43, 3433-3439.
[17] Zhiya Ma, Yueping Guan, Xianqiao Liu and Huizhou Liu, Covalent Immobilization of Albumin on Magnetic Poly (methyl methacrylate-divylbenzene-glycidyl methacrylate) Microspheres, Polymer for Advanced Technology, 2005, 16, 554-558.
[18] Zhiya Ma, Yueping Guan, Junguo Liu and Huizhou Liu, Synthesis of Monodisperse Nonporous Crosslinked Polyglycidyl methacrylate Particles with Metal Affinity Ligands for Protein Adsorption, Polymer International, 2005, 54 (11) , 1502-1507
[20] Xianqiao Liu, Yueping Guan, Zhiya Ma, Rui Shen, Huizhou Liu. Study on Lipase Immobilization on Novel Magnetic Supports. Journal of Chromatography B, 2005,822,91-97.
[21] Xianqiao Liu, Yueping Guan, Hiuzhou Liu, Zhiya Ma, Yu Yang and Xiaobing Wu. Preparation and Characterization of Magnetic Polymer Nanospheres with High Protein Binding Capacity. Journal of Magnetism and Magnetic Materials. 2005, 293 (1), 111-118.
[22] Zhiya Ma, Yueping Guan, Xianqiao Liu and Huizhou Liu, Preparation and Characterization of Micron-sized Non-porous Magnetic Polymer Microspheres with Immobilized Metal Affinity Ligands by Modified Suspension Polymerization, Journal of Applied Polymer Science, 2005. 96, 2174–2180
[23] Xianqiao Liu, Yueping Guan, Zhiya Ma, and Huizhou Liu. Surface Modification and Characterization of Magnetic Polymer Nanospheres Prepared by Miniemulsion Polymerization. Langmuir, 2004, 20(23): 10278-10282.
[24] Xianqiao Liu, Yueping Guan, Yu Yang, Zhiya Ma, Xiaobing Wu and Huizhou Liu. Preparation of Superparamagnetic Immunomicrospheres and Application for Antibody Purification. Journal of Applied Polymer Science, 2004, 94 (5): 2205-2211.
[25] D. Bozhinova, B. Galunsky, Yueping Guan, M. Franzreb, R. Köster & V. Kasche, Evaluation of magnetic polymer micro-beads as carriers of immobilized biocatalysts for selective and stereoselective transformations, Biotechnology Letters, 2004, 26: 343–350.

近五年申请或授权的代表性专利:
[1]官月平、王强、刘刚、戈莹、谢立,“一种合成磁性聚合物微球的方法”,中国发明专利申请号201010168903.2(2010);
[2]官月平、赖仙红、谢立、刘刚 、戈莹,“一种磁性免疫检测方法”, 中国发明专利申请号:200910238431.0(2009);
[3]Matthias Franzreb /Yueping Guan and Bozhinova Daniela, A Process for Preparation of Magnetic Polymer Particles. 欧洲发明专利(EP1391899)/ 德国专利(DE10237742)(2005年授权);
[4]官月平,刘会洲,安振涛,柯家俊,陈家镛,“超顺磁性聚合物微球及其制造方法”,中国发明专利ZL 98124516.1 (2004年授权);
[5]官月平,刘会洲,安振涛,戴冬煦,陈家镛,“从流体中分离磁性颗粒的连续式高梯度磁分离方法及装置”,中国发明专利ZL 99107814.4(2004年授权).